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What Is Liver Transplant
& Who Needs It

Multidisciplinary care

What Is A Liver Transplant?

A liver transplant is surgery that replaces a diseased or failing liver with a healthy donor liver or an appropriate portion of a donor liver, depending on the transplant pathway. It is considered for selected patients whose condition warrants transplantation.

1

Replacing liver function

The aim is to restore liver function when the patient’s own liver can no longer adequately perform its roles.

2

Living donor pathway

A suitable living donor may donate a portion of the liver after medical and other required evaluation.

3

Deceased donor pathway

A deceased-donor liver becomes available through the applicable organ-donation and allocation system.

4

Major surgery

Liver transplantation requires major surgery and coordinated perioperative, critical-care and long-term medical support.

5

Individual decision

Not every patient with chronic liver disease needs a transplant.

6

Long-term care

Transplantation is followed by long-term medicines, monitoring and specialist follow-up.

What Is a Liver Transplant?

A liver transplant replaces a diseased or failing liver with a donor liver or appropriate donor graft for selected patients whose condition warrants transplantation.

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Who May Need A Liver Transplant?

Transplant evaluation may be considered in advanced or decompensated liver disease, acute liver failure, selected liver cancers and certain metabolic, genetic or other conditions. Suitability is determined by individual specialist assessment.

1

Decompensated cirrhosis

Advanced liver disease with complications may lead to transplant evaluation.

2

Acute liver failure

Some severe cases require urgent specialist evaluation.

3

Selected liver cancers

Transplantation may be considered for appropriately selected patients based on tumour and liver characteristics.

4

Selected other conditions

Certain metabolic, genetic or other liver-related conditions may warrant evaluation depending on the clinical situation.

Who Needs a Liver Transplant?

Selected patients with advanced or decompensated liver disease, acute liver failure, certain liver cancers or other appropriate conditions may be considered for transplant evaluation.

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How Is Someone Evaluated For A Liver Transplant?

Evaluation combines specialist consultation, review of the liver condition, laboratory and imaging assessment, assessment of overall health and, when relevant, evaluation of a potential living donor.

1

Consultation

Initial specialist consultation and review of medical records.

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2

Medical Evaluation

Assessment of liver disease severity and current clinical condition.

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3

Reports Assessment

Review of available laboratory tests and imaging, with further investigations where indicated.

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4

Donor Tests

Donor assessment when a living-donor pathway is being considered.

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5

Transplant Process

Suitability review and discussion of the appropriate transplant pathway.

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6

Post Transplant Care

Plan next steps, follow-up and any additional evaluation.

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How Is Someone Evaluated for a Liver Transplant?

Evaluation combines specialist consultation, review of the liver condition, laboratory and imaging assessment, overall health assessment and, when relevant, potential-donor evaluation.

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What Tests Are Done Before A Liver Transplant?

The exact work-up varies, but the supplied transplant material identifies blood tests, imaging, assessment of liver severity, review of other organ systems and medical conditions, infection/other screening, nutrition and donor work-up as relevant components.

Donor assessment

Blood tests

Liver function, blood counts, kidney function and other relevant clinical factors.

Recipient assessment

Imaging

Liver, vessels, anatomy and other findings relevant to treatment planning.

Compatibility and graft assessment

Cardiopulmonary assessment

Overall fitness for major surgery when additional assessment is indicated.

Assess-the-liver2

Infection & other screening

Testing arranged according to transplant evaluation and clinical situation.

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Nutrition

Nutritional status and frailty can influence pre- and posttransplant care.

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Donor work-up

A potential living donor undergoes independent evaluation focused on donor safety and suitability.

Our Doctors

Meet Our Liver Transplant Surgeons & Hepatology Team

Dr. Manoj Shrivastav, HOD at Multi-Organ Transplant

Dr. Manoj Shrivastav

MBBS · DNB (General Surgery) · Fellowship in Liver Transplantation, Global Hospital, Chennai

Dr. Manoj Shrivastav is a liver transplant surgeon at Ruby Hall Clinic, Pune, and currently leads the multi-organ transplant programme. He has personally completed over 200 liver transplants in Pune, 100 of them in the past year alone, with a survival rate above 95% and a one-year survival rate of 92% across his transplant series.

800+
Liver transplants
in Pune
95%+
Survival
rate
92%
One-year
survival rate

He is equipped to handle acute surgical emergencies and trauma across a variety of scenarios, has performed major liver resections for hepatocellular carcinoma and cholangiocarcinoma, and believes a successful transplant depends on excellent teamwork across the entire clinical team — not one surgeon alone.

Meet the Team

Frequently Asked Questions

Is a liver transplant always needed for cirrhosis?

No. Many patients with cirrhosis are managed without transplantation. Evaluation is considered in selected advanced or decompensated disease.

How does a liver transplant work?

The diseased liver is removed and replaced with a donor liver or suitable donor graft, with restoration of blood flow and bile drainage.

What are the indications for liver transplant?

Common categories include advanced/decompensated liver disease, acute liver failure, selected liver cancers and selected metabolic or genetic conditions.

How long does the liver transplant process take?

Timing varies by evaluation findings, donor pathway, waiting-list requirements and individual clinical circumstances.

Can liver cancer be treated with a liver transplant?

For selected patients, transplantation may form part of liver cancer treatment. Eligibility depends on tumour and liver characteristics.

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Talk to the liver team

Need to discuss liver transplant options?

Speak with the Liver Sciences & Multi-Organ Transplant team at Ruby Hall Clinic, Pune. Bring available medical
records, imaging, laboratory reports and previous treatment details where available.